10x ROAS with 500% increased spend

Overview

Twist Bioscience is a global synthetic DNA and biotechnology company that powers genomics, drug discovery, and industrial biotech research.
As demand for gene synthesis and DNA data storage solutions expanded, Twist Bioscience needed a smarter digital funnel to convert high-value enterprise traffic into qualified sales inquiries across pharma, academia, and biotech manufacturing.

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https://www.twistbioscience.com/

The problem

Before partnering with Mickson Growth, Twist Bioscience’s paid search and tracking systems were not set up to support their enterprise sales goals:

  • Campaigns were not aligned to specific research segments or product lines
  • Cost per acquisition was very high
  • No clear attribution between ad spend and revenue for ROAS

Their marketing team was spending heavily on traffic that rarely converted into qualified enterprise opportunities. Average CPL exceeded $1000, and conversion visibility was minimal.

The solution

Here’s what we did:

  • Rebuilt Google Ads from the ground up around specific verticals
  • Designed custom landing pages focused on each solution area (synthetic DNA, NGS, biopharma tools)
  • Integrated Marketo, Tableau, & GA4 to capture and attribute enterprise leads accurately
  • Leverage Google's AI Smart bidding alogorithm to generate quality buyers
  • Optimized form flows and CTAs for shorter submission paths

This revamped infrastructure gave Twist Bioscience a fully tracked B2B funnel capable of scaling to enterprise-level deal sizes.

The result

Twist Bioscience saw a dramatic improvement in lead quality and ROAS:

  • Improved ROAS to 10x while scaling budget by 500% quarter over quarter
  • Reduced cost per acquisition by 45%

By pairing data-driven targeting with customized landing experiences, Mickson Growth transformed Twist Bioscience’s digital marketing into a scalable, revenue-aligned pipeline engine for the biotech sector.